The two-volume proceedings CCIS 1613 + 1614 constitute revised selected papers from the 6th International Conference on Advances in Computing and Data Sciences, ICACDS 2022, which was held in Kurnool, India in April 2022.The total of 69 full papers presented in the proceedings was carefully reviewed and selected from 411 submissions. The papers focus on advances of next generation computing technologies in the areas of advanced computing and data sciences.