Botulinum Neurotoxins (kartoniertes Buch)
Botulinum Neurotoxins
Current Topics in Microbiology and Immunology 364
Erschienen am
29.01.2015
Bibliographische Informationen
ISBN/EAN: 9783642448898
Sprache: Englisch
Seiten: viii, 324 S.
Auflage: 1. Auflage 2015
Bindung: kartoniertes Buch
Beschreibung
The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.
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