Improving the efficiency of turbines for power plants and aircraft engines is an increasingly important research subject. Ternary Mo-Si-B alloys, consisting of a molybdenum solid solution (Moss) phase and two intermetallic phases Mo5SiB2 (T2) and Mo3Si, are able to combine balanced room temperature fracture toughness, high temperature creep strength and good oxidation performance. However, the high density of this class of alloys is a drawback when used as a turbine blade material. Therefore, the present thesis deals with vanadium as a potential alloying partner for density optimized Mo-based alloys.